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| 1968 SCHEDULEOverall 7-2-1Home 5-1Away 1-1-1Neutral 1-0 |
| Date | Opponent / Event | Location | Time / Result | Media | |
| Sat., Sep. 21 | vs. Oklahoma |
Notre Dame, Ind. | W, 45-21 | More | |
| Sat., Sep. 28 | vs. Purdue |
Notre Dame, Ind. | L, 37-22 | TV: ABC (Regional) | More |
| Sat., Oct. 5 | at Iowa |
Iowa City, Iowa | W, 51-28 | More | |
| Sat., Oct. 12 | vs. Northwestern |
Notre Dame, Ind. | W, 27-7 | More | |
| Sat., Oct. 19 | vs. Illinois |
Notre Dame, Ind. | W, 58-8 | More | |
| Sat., Oct. 26 | at Michigan State |
East Lansing, Mich. | L, 21-17 | TV: ABC | More |
| Sat., Nov. 2 | vs. Navy |
Philadelphia, Pa. | W, 45-14 | More | |
| Sat., Nov. 9 | vs. Pittsburgh |
Notre Dame, Ind. | W, 56-7 | More | |
| Sat., Nov. 16 | vs. Georgia Tech |
Notre Dame, Ind. | W, 34-6 | More | |
| Sat., Nov. 30 | at USC |
Los Angeles, Calif. | T, 21-21 | TV: ABC | More |
Schedule Key Home Event Away Event